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Francis Crick Quotes and Sayings

I hope you find great value in these Quotes by Francis Crick from my large collection of motivational and inspirational quotes and sayings.

A comparison between the triplets tentatively deduced
by these methods with the changes in amino acid sequence
produced by mutation shows a fair measure of agreement.
- Francis Crick

Unfortunately it makes the unambiguous determination
of triplets by these methods much more difficult than
would be the case if there were only one triplet for each amino acid.
- Francis Crick

If poly A is added to poly U, to form a double or triple helix,
the combination is inactive.
- Francis Crick

This seems highly likely, especially as it has been
shown that in several systems mutations affecting the
same amino acid are extremely near together on the genetic map.
- Francis Crick

 

We are sometimes asked what the result would be if
we put four +'s in one gene.
To answer this my colleagues have recently put together
not merely four but six +'s.
- Francis Crick

How is the base sequence, divided into codons? There
is nothing in the backbone of the nucleic acid,
which is perfectly regular, to show us how to group the bases into codons.
- Francis Crick

If the code does indeed have some logical foundation
then it is legitimate to consider all the evidence,
both good and bad, in any attempt to deduce it.
- Francis Crick

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For simplicity one can think of the + class as having
one extra base at some point or other in the genetic message and the -
class as having one too few.
- Francis Crick

We've discovered the secret of life.
- Francis Crick

A final proof of our ideas can only be obtained by
detailed studies on the alterations produced in the
amino acid sequence of a protein by mutations of the type discussed here.
- Francis Crick

It has yet to be shown by direct biochemical methods,
as opposed to the indirect genetic evidence mentioned earlier,
that the code is indeed a triplet code.
- Francis Crick

It now seems certain that the amino acid sequence of
any protein is determined by the sequence of bases
in some region of a particular nucleic acid molecule.
- Francis Crick

If, for example, all the codons are triplets,
then in addition to the correct reading of the message,
there are two incorrect readings which we shall obtain
if we do not start the grouping into sets of three at the right place.
- Francis Crick

The balance of evidence both from the cell-free system
and from the study of mutation,
suggests that this does not occur at random,
and that triplets coding the same amino acid may well be rather similar.
- Francis Crick

Do codons overlap? In other words, as we read along
the genetic message do we find a base which is a member
of two or more codons? It now seems fairly certain
that codons do not overlap.
- Francis Crick

Attempts have been made from a study of the changes
produced by mutation to obtain the relative order of
the bases within various triplets,
but my own view is that these are premature until there
is more extensive and more reliable data on the composition of the triplets.
- Francis Crick

The meaning of this observation is unclear,
but it raises the unfortunate possibility of ambiguous triplets;
that is,
triplets which may code more than one amino acid.
However one would certainly expect such triplets to be in a minority.
- Francis Crick

It is one of the more striking generalizations of biochemistry -
which surprisingly is hardly ever mentioned in the biochemical textbooks -
that the twenty amino acids and the four bases,
are, with minor reservations, the same throughout Nature.
- Francis Crick

It now seems very likely that many of the 64 triplets,
possibly most of them, may code one amino acid or another,
and that in general several distinct triplets may code one amino acid.
- Francis Crick

Moreover the incorporation requires the same components
needed for protein synthesis,
and is inhibited by the same inhibitors.
Thus the system is most unlikely to be a complete artefact
and is very probably closely related to genuine protein synthesis.
- Francis Crick

It seems likely that most if not all the genetic information
in any organism is carried by nucleic acid -
usually by DNA,
although certain small viruses use RNA as their genetic material.
- Francis Crick

It would appear that the number of nonsense triplets is rather low,
since we only occasionally come across them.
However this conclusion is less secure than our other
deductions about the general nature of the genetic code.
- Francis Crick

Do not overrate what you have received, nor envy others.
He who envies others does not obtain peace of mind.
- The Buddha

Let not him who is houseless pull down the house of another,
but let him work diligently and build one for himself,
thus by example assuring that his own
shall be safe from violence when built.
- Abraham Lincoln

One of the greatest cause of unhappiness -
perhaps even the only cause of unhappiness - is comparison.
I remember as a young child hearing my mother say,
"Comparisons are odious."
That is one of the oldest sayings in the English language,
and one of the most important.
- Jonathan Lockwood Huie

Love is the total absence of fear.
Love asks no questions.
Its natural state is one of extension and expansion,
not comparison and measurement.
- Gerald Jampolsky

Religion is more than life. Remember that his own religion
is the truest to every man even if it stands low
in the scales of philosophical comparison.
- Mohandas (Mahatma) Gandhi

How blunt are all the arrows of thy quiver in comparison with those of guilt.
- Robert Blair

Our political differences, now matter how sharply they are debated,
are really quite narrow in comparison to the remarkably
durable national consensus on our founding convictions.
- John McCain

Life - and I don't suppose I'm the first to make this comparison -
is a disease: sexually transmitted,
and invariably fatal.
- Neil Gaiman

I really reject that kind of comparison that says,
Oh, he is the best.
This is the second best.
There is no such thing.
- Mikhail Baryshnikov

This nation has been drifting back in comparison with
the rest of the world for the last 20 years in education.
- Roy Romer

I performed adequately at school, but in comparison to my older brother,
who set the record for the highest cumulative average for our high school,
my performance was decidedly mediocre.
- Steven Chu

We all dream; we do not understand our dreams,
yet we act as if nothing strange goes on in our sleep minds,
strange at least by comparison with the logical,
purposeful doings of our minds when we are awake.
- Erich Fromm

Jealousy is the fear of comparison.
- Max Frisch

Composing a piece of music is very feminine.
It is sensitive, emotional, contemplative.
By comparison, doing housework is positively masculine.
- Barbara Kolb

The Athanasian Creed is to me light and intelligible
reading in comparison with much that now passes for science.
- Samuel Butler

I think that, in comparison, New Yorkers and Northerners are so guarded.
- Genevieve Gorder

That is to say, nature's laws are causal;
they reveal themselves by comparison and difference,
and they operate at every multivariate space/time point.
- Edward Tufte

I think my comparison with Shane would be a loner.
I always got the impression that she wasn't scared to be alone.
She enjoys it.
I can relate to that.
- Katherine Moennig

No man is happy but by comparison.
- Thomas Shadwell

Get to know other worlds, if only for comparison.
I am near, too near for him to dream of me.
- Wislawa Szymborska

There is no comparison between that which is lost by
not succeeding and that which is lost by not trying.
- Francis Bacon

Intolerance respecting other people's religion is toleration
itself in comparison with intolerance respecting other people's art.
- Wallace Stevens

Today the salaries of stars are astronomical in comparison with the 20's,
but the high cost of today's living and taxes takes
a huge bite out of these salaries.
- Pola Negri

It is only through contact and comparison that the
relative value or worthlessness of the various cultural
elements can be clearly and critically seen and understood.
- Hu Shih

The only relevant test of the validity of a hypothesis
is comparison of prediction with experience.
- Milton Friedman

Beauty is a relation, and the apprehension of it a comparison.
- Gerard Manley Hopkins

I did a comparison of a school of architects known as the New York Five.
I compared their articulation of wall surfaces,
which I enjoyed very much.
- Parker Stevenson

A man's thinking goes on within his consciousness in
a seclusion in comparison with which any physical seclusion
is an exhibition to public view.
- Ludwig Wittgenstein

The worst excesses of the Congress of the 1980s pale
in comparison with what is going on in Washington today.
- Marty Meehan

If I remember rightly Holland for instance has something like 45,
and it's a much smaller country.
In comparison we have very few and they are very badly financed.
- Richard Rogers

True love makes the thought of death frequent,
easy, without terrors; it merely becomes the standard of comparison,
the price one would pay for many things.
- Stendhal

Death comes at you no matter what you do in this life,
and to equate drugs with death is a facile comparison.
- Jerry Garcia

Comparison is a death knell to sibling harmony.
- Elizabeth Fishel

These seem to me so ambiguous, so vague,
so easily misunderstood in comparison to genuine music,
which fills the soul with a thousand things better than words.
- Felix Mendelssohn

In comparison with a loving human being,
everything else is worthless.
- Hugh MacLennan

There is no comparison between the training here and the training in Israel.
- Isaac Yeffet

It is very easy to overestimate the importance of our
own achievements in comparison with what we owe others.
- Dietrich Bonhoeffer

Reality seems valueless by comparison with the dreams of fevered imaginations;
reality is therefore abandoned.
- Emile Durkheim

If the September 11 terror attack is supposed to constitute
a caesura in world history,
it must be able to stand comparison to other events
of world historical impact.
- Jurgen Habermas

In the absence of that, I am happy to play solo,
but I don't think there is any comparison.
- Derek Bailey

Laughter is nothing else but sudden glory arising from
some sudden conception of some eminency in ourselves,
by comparison with the infirmity of others,
or with our own formerly.
- Thomas Hobbes

Happiness in the present is only shattered by comparison with the past.
- Douglas Horton

The massive bulk of the earth does indeed shrink to
insignificance in comparison with the size of the heavens.
- Nicolaus Copernicus

Your meditations may be as profound,
as exalted,
as devout as you like; you may practise every pious exercise you can manage,
but all this is as nothing in comparison with the Blessed Sacrament.
What we do may be godly, but this sacrament is God Himself!
- Johannes Tauler

In comparison with other men of their time,
the Americans were distinguished by the possession
of new political and social ideas,
which were destined to be the foundation of the American commonwealth.
- Albert Bushnell Hart

This communication alone, by the comparison of the antagonisms,
rivalries, movements which give birth to decisive moments,
permits the evolution of the soul, whereby a man realizes himself on earth.
It is impossible to be concerned with anything else in art.
- Robert Delaunay

But sequence comparisons simply can't account for the
development of complex biochemical systems any more
than Darwin's comparison of simple and complex eyes
told him how vision worked.
- Michael Behe

I was trained as a neurologist, and then I went into the theater,
and if you're brought up to think of yourself as a
biological scientist of some sort,
pretty well everything else seems frivolous by comparison.
- Jonathan Miller

But, in fact, there is nothing that can bring you closer
to fearlessness about everything else in the world than being a parent -
because everyday fears - like not being approved of -
pale by comparison to the fears you have about your children.
- Arianna Huffington


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- Jonathan Lockwood Huie

 


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